I had an '05 TSX before I got my 335, ride quality is about the same as the TL. I previously test drove both the TL and the IS350. You can't go wrong with the TL; it offers a very good ride, has nicely appointed interiors, and a very good price considering all the included options. Although it doesn't come in MT, I prefer the IS350 because its a RWD and the ride is a lot more smoother than the TL. The gear change on the Lexus' automatic trasmission is a lot better than Acura's AT. If you don't have a specific budget and don't care for MT, I'll recommend you to go with the IS350. Just test drive both and go from there
