In my mind the E350 is a "grown-up" car, and the visual image would be akin to a young child wearing a business suit. I've read several reviews that say the E-class is a very safe and nice car, but also very boring. It's meant to get the family from point A to point B in safe luxury, no real thrills besides the AMG. Besides, you get a car for the way it drives, not quadra-zoned climate control.
I think you should tell your mom to look at a similar 5 Series, because its a BMW, and by nature they have to handle well.
Or just tell her to get a 335i