Originally Posted by Chewy734
Magento is more powerful and gives more options than OSCommerce, imo. That being said, it's more of a pain to install and configure payment options on it. I'm using Magento on my business site. Once you have it working, it's really nice though.
Send me a PM if you need more info.
This, it largely depends on what he's trying to sell and how he's planning on going about it.
90% of the time, standard cut and paste templates and the simple approach will work. But if you're looking to make things a little more customizable and actually are making this a LARGE longterm project....go big or go home.
Your friend largely needs to figure out how much time he wants to put into this upfront.