Four childhood friends from NYC (two of them brothers). One becomes a movie star, all four move to LA, and let the hilarity ensue. It's exactly what you wish your life was like if you and three of your closest buddies lived together, had endless funds, and nothing to really do each day.
(it's like college, but you're not poor)
Abrasive, arrogant, yet brilliant doctor who heads a team that diagnoses the medical problems that no one else can figure out.
If you don't have HBO, you can get the previous seasons of Entourage on DVD. Rent it, or hell just buy it.