I've been using the Nikon 18-200 VR lens for a while now and it's great. It's practically a do-it-all lens which means you don't have to carry around multiple lenses, you're not constantly swap lenses, you don't have to worry about dust getting on the sensor during lens swaps, and you (almost) always have the right lens at the right time. For what you get it's not overly large or heavy, but it isn't a lightweight by any means. The VR mode is great for no flash low light shots.
The downside is it's price. If you consider it's price in perspective of two different lenses of the same quality, it's not such a bad deal. Something to consider.