I wouldn't think a S3 in stock form would work with a 335i in acceleration. Standing start it may hold a 335i to about 80~90mph (high 3rd gear) but after this point the 335i will steadily pull chunks out of it.
On a twisty road is where the S3 will stand a very good chances of winning. For you lot in the states who haven't sampled the mighty S3's handling balance would be pleasantly surprised as to how grippy and adjustable it is.
No the only car which will have the 335i concerned is the TTS, the spec of this little car is very impressive and having driven the TT2.0fwd I know just how light on it's feet is feels.