Here's a comparison set. Both pics shot with the same specs: 70-300L f5 1/50s 12800 ISO. The first is MSNR, the second is PP'd with ACR using NR. There is a difference in focal point, unfortunately, but this is about noise anyway.
Not a lot of difference, but the MSNR shot took much less work to get is clean. And in the full image I think the detail is better in the MSNR version.