Not really a guessing game. As long as temps were not extreme and a few runs were done to get some kind of adaptation average happened 265 is really low for catless, intake/drop in and a tune on a dynojet with 93 octane.
I would ask you when did you have your plugs changed? I am guessing you are not hitting your timing targets which is the primary way a tune increases power. WIthout good plugs you will knock before ever hitting the targets