I've had the back end come out a tad with an S5 upshift from 2nd to 3rd. Caught it and not a big deal. It was mentioned earlier, never had an issue from 3rd to 5th going up or down.
Its those certain places where you take advantage of the DCT to drop down into 2nd. So I just leave it in S4 and I have been happy. And your expensive and non-replacable gears take less of a pounding.
2013 F30 328i Melbourne Red
2011 E90 M3 Monte Carlo Blue
2004 E46 M3 Imola Red