If you value reliability Range Rover or Land Rovers are not to be placed on your list.
Please note that the Lexus Rx400 comes with a warning NOT to be taken off road (electric motor shorts danger).
For amazing off road performance and good on road manner, plus nice interior place the VW Tuareg on your list - it has also had some teething issues with reliability but it is head and shoulders above the RR on that topic.
If the MDX is on your list, your off road requirements are therefore not that great. In such a case consider as well the X5, much better package than the MDX from a handling/engine/interior/brakes perspective.
2016 435 xdrive GC white on black leather interior, Msport1, Msport2, premium package
2015 Lincoln MKX, silver on brown leather, premium package - that's right! Techno-Groovy baby